UMDNJ-Rutgers University
CounterACT Research
Center of Excellence

Designing therapies to counteract chemical terrorism.

Joshua P. Gray, Ph.D.

Assistant Professor
Pharmacology & Toxicology
Ernest Mario School of Pharmacy
Rutgers University

Email: gray@eohsi.rutgers.edu
Room: 441 EOHSI
Phone: 732-445-0188
Fax: 732-445-0119
Web page

B.S. Biochemistry & Molecular Biology, Pennsylvania State University
Ph.D. Pathobiology, Pennsylvania State University
Postdoctoral, Mechanisms of Oxidative Stress, UMDNJ-Robert Wood Johnson Medical School

Education & Training Core, UMDNJ-Rutgers University CounterACT Center of Excellence

Research Interests:

Mechanisms of dermatoxicity, wound healing, cell growth regulation, peroxisome proliferators, role of redox cycling in chemical toxicity, reactive oxygen intermediates, paraquat toxicity, microsensors in toxicity, toxicogenomics.

Recent Publications:

Gray JP, Heck DE, Mishin V, Smith PJS, Hong JY, Thiruchelvam M, Cory-Slechta DA, Laskin DL, and Laskin JD. Paraquat increases cyanide-insensitive respiration in murine lung epithelial cells by activating an NAD(P)H: Paraquat Oxidoreductase: Identification of the enzyme as thioredoxin reductase. (2007) J Biol Chem, epub ahead of print. [abstract]

Gray JP, Davis JW, Gopinathan L, Leas TL, Thompson JT, Vanden Heuvel JP. The ribosomal protein rpL11 associates with and inhibits the transcriptional activity of peroxisome proliferator-activated receptor-alpha. (2006) Toxicol Sci, 89 (2): 535-546. [abstract]

Gray JP, Burns KA, Leas TL, Perdew GH, Vanden Heuvel JP. Regulation of peroxisome proliferator-activated receptor alpha by protein kinase C. (2005) Biochemistry, 44 (30): 10313-10321. [abstract]

Tien ES, Gray JP, Peters JM, Vanden Heuvel JP. Comprehensive gene expression analysis of peroxisome proliferator-treated immortalized hepatocytes: identification of peroxisome proliferator-activated receptor alpha-dependent growth regulatory genes. (2003) Cancer Res, 63 (18): 5767-5780. [abstract]

Gray JP, Leas TL, Obert E, Brown D, Clark GC, Vanden Heuvel JP. Evidence of aryl hydrocarbon receptor ligands in Presque Isle Bay of Lake Erie. (2003) Aquat Toxicol, 64 (3): 343-358.

Copyright © 2006 Joshua P. Gray